Niche derived oligodendrocyte progenitors: a source of rejuvenation or complementation for local oligodendrogenesis?
نویسندگان
چکیده
منابع مشابه
Niche derived oligodendrocyte progenitors: a source of rejuvenation or complementation for local oligodendrogenesis?
With the recent revelations that strikingly plastic cytogenic and migratory processes take place in the adult mammalian brain, it cannot anymore be considered as an organ static or utterly unequipped against injury. The Subependymal Zone (SEZ) or otherwise called with its embryonic equivalent as the subventricular zone, is one major cytogenic area located at the lateral wall of the lateral vent...
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Oligodendrocyte precursor cells (OPCs) express NMDA receptors (NMDARs) and form synapses with glutamatergic neurons throughout the CNS. Although glutamate influences the proliferation and maturation of these progenitors in vitro, the role of NMDAR signaling in oligodendrogenesis and myelination in vivo is not known. Here, we investigated the consequences of genetically deleting the obligatory N...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2013
ISSN: 1662-5102
DOI: 10.3389/fncel.2013.00188